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Biosystems ; 224: 104827, 2023 Feb.
Article in English | MEDLINE | ID: covidwho-2165113

ABSTRACT

After the detection of coronavirus disease 2019 (Covid-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, Hubei Province, China in late December, the cases of Covid-19 have spiralled out around the globe. Due to the clinical similarity of Covid-19 with other flulike syndromes, patients are assayed for other pathogens of influenza like illness. There have been reported cases of co-infection amongst patients with Covid-19. Bacteria for example Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae, Mycoplasma pneumoniae, Chlamydia pneumonia, Legionella pneumophila etc and viruses such as influenza, coronavirus, rhinovirus/enterovirus, parainfluenza, metapneumovirus, influenza B virus etc are identified as co-pathogens. In our current effort, we develop and analysed a compartmental based Ordinary Differential Equation (ODE) type mathematical model to understand the co-infection dynamics of Covid-19 and other influenza type illness. In this work we have incorporated the saturated treatment rate to take account of the impact of limited treatment resources to control the possible Covid-19 cases. As results, we formulate the basic reproduction number of the model system. Finally, we have performed numerical simulations of the co-infection model to examine the solutions in different zones of parameter space.


Subject(s)
COVID-19 , Coinfection , Influenza, Human , Respiratory Tract Infections , Virus Diseases , Viruses , Humans , SARS-CoV-2 , Influenza, Human/epidemiology , Influenza, Human/diagnosis , COVID-19/epidemiology , Coinfection/epidemiology , Coinfection/diagnosis , Respiratory Tract Infections/diagnosis , Respiratory Tract Infections/microbiology , Models, Theoretical
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